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KMID : 0360220100510111453
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Journal of the Korean Ophthalmological Society
2010 Volume.51 No. 11 p.1453 ~ p.1458
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The Short?Term Efficacy of Intravitreal Ranibizumab in the Treatment of Diabetic Macular Edema
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Kong Seok-Joon
Yang Ji-Wook
Jee Dong-Hyun
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Abstract
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Purpose: To evaluate the short-term effect of an intravitreal injection of ranibizumab in the treatment of diabetic macular edema.
Methods:Eighteen eyes of 18 patients who underwent intravitreal ranibizumab injection for the treatment of diabetic macular edema between March 1 and November 30, 2009 were retrospectively evaluated. Complete ophthalmic examinations including best corrected visual acuity and optical coherence tomography (OCT) were performed at baseline and follow-up visits at one and three months.
Results:The mean visual acuity improved from logMAR 0.74 ± 0.45 at baseline to logMAR 0.44 ± 0.26 at one month and to logMAR 0.42 ± 0.23 at three months (p < 0.05). The mean central macular thickness decreased from 429.5 ± 71.9 μm at baseline to 299.9 ± 81.2 μm at one month and to 284.6 ± 82.6 μm at three months (p < 0.05). No adverse side effects were observed following the injections.
Conclusions:The observed macular edema and visual acuity improvements demonstrated that intravitreal ranibizumab injection may be useful for the treatment of patients with diabetic macular edema.
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KEYWORD
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Diabetic macular edema, Ranibizumab
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